Etude sur les applications nutritionnelles et thérapeutiques de la spiruline. 


Références bibliographiques démontrant l'intérêt nutritionnel de la spiruline : 

1. Abdulqader G, Barsanti L, Tredici M. Harvest of Arthrospira platensis from Lake Kossorom (Chad) and its household usage among the Kanembu. J Appl Phycol. 2000;12:493-498.

2. Belay A, Ota Y, Miyakawa K, Shimamatsu H. Production of high quality Spirulina at Earthrise Farms. In: Phang et al., eds. Algal Biotechnology in the Asia-Pacific Region. University of Malaya; 1994:92-102.

3. Belay A, Kato T, Ota Y. Spirulina (Arthrospira): potential application as an animal feed supplement. J Appl Phycol. 1996;8:303-311.

4. Belay A. Mass culture of Spirulina outdoors: the Earthrise Farms experience. In: Vonshak A, ed. Spirulina platensis (Arthrospira) Physiology, Cell Biology and Biotechnology. London: Taylor & Francis; 1997;131-158.

5. Chamorro G. Toxicological research on the alga Spirulina. Report: United Nations International Development Organization (UNIDO) UF/MEX/78/048, 1980.

6. Salazar M, Chamorro G, Salazar S, Steele C. Effect of Spirulina maxima consumption on reproductive and peri- and postnatal development in rats. Food Chem Toxicol. 1996;353-359.

7. Chamorro G, Salazar S, Castillo L, Steele C, Salazar M. Reproductive and peri- and postnatal evaluation of Spirulina maxima in mice. J Appl Phycol. 1997;9:107-112.

8. Salazar M, Martinez E, Madrigal E, Ruiz LE, Chamorro G. Subchronic toxicity study in mice fed Spirulina. J Ethnopharmacol. 1998;62:235-241.

9. Belay A. Current knowledge on potential health benefits of Spirulina. J Appl Phycol. 1993;5:235-241.

10. Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol. 1994;40:431-441.

11. Liu L, Guo B, Ruan J, Dai X, Chen L, Wu B. Study on effect and mechanism of polysaccharides on Spirulina platensis on body immune functions improvement. Marine Sci. 1991.6:44-49.

12. Qureshi MA, Kidd MT, Ali RA. Spirulina platensis extract enhances chicken macrophage functions after in vitro exposure. J Nutr Immunol. 1995;3:35-44.

13. Baojiang G. Study on effect and mechanism of polysaccharides of Spirulina platensis on body immune functions improvement. Book of Abstracts. Second Asia Pacific Conference on Algal Biotechnology. 1994;24.

14. Qureshi MA, Ali RA, Hunter RL. Immunomodulatory effects of Spirulina platensis supplementation in chickens. Proceedings of the 44th Western Poultry Disease Conference. 1995;117-121.

15. Isobe K, Hayashi O, Hirahashi T, Katoh T, Okuwaki Y. Bactericidal activity of mouse macrophages stimulated with Spirulina extracts. J Kagawa Nutr. 1995;26:61-66.

16. Qureshi MA, Garlich J, Kidd M. Dietary Spirulina platensis enhances humoral and cell-mediated immune function in chickens. Immunopharmacol Immunotoxicol. 1996;18:465-476.

17. Qureshi MA, Ali RA. Spirulina platensis exposure enhances macrophage phagocytic function in cats. Immunopharmacol Immunotoxicol. 1996;18:457-463.

18. Duncan P, Klesius P. Effects of Spirulina on specific and nonspecific immune responses in channel catfish. J Aquatic Animal Health. 1996;8:308-313.

19. Lee K. Spirulina and immunological activity of cultured prawn. Book of Abstracts. Second Asian Pacific Phycological Forum. 1999; M-25.

20. Mao TK, Van De Water J, Gershwin ME. Effect of Spirulina on the secretion of cytokines from peripheral blood mononuclear cells. J Medicinal Food. 2000;3:135-140.

21.Saeki Y, Matsumoto M, Hayashi A, Azuma I, Toyoshima K Seya T. The effect of Spirulina hot water extract to the basic immune activation. Summary of paper presented at the 30th Annual Meeting of the Japanese Society for Immunology. November 14-16, 2000.

22. Saeki Y, Matsumoto M, Hayashi A, Azuma I, Toyoshima K, Seya T. Innate immunotherapy for cancer: anti-tumor effects of BCG-CWS in implanted tumor model. Summary of a paper presented at the 59th Annual Meeting of the Japanese Cancer Association. October 4-6, 2000.

23. Evets LB, Belookaya T, Lyalikov S, Orehov SD, Shipulin E. Means to normalize the levels of immnoglobulin E. Russian Federation Committee of Patents and Trade. Patent Number (19)RU (11)20005486 C1 (51) 5 A 61K35/80. 1994. 1-page translation.

24. Yang H, Lee E, Kim H. Spirulina platensis inhibits anaphylactic reaction. Life Sciences. 1997;61:1237-1244.

25. Kim H, Lee E, Cho H, Moon Y. Inhibitory effect of mast cellmediated immediate-type allergic reactions in rats by Spirulina. Biochem Phamacol. 1998;55:1071-1076.

26. Gonzalez R, Rodriguez S, Romay C, Ancheta O, Gonzalez A, Armesto J, Remirez D, Merino N. Anti-inflammatory activity of phycocyanin extract in acetic acid-induced colitis in rats. Pharmacol Res. 1999;39:55-59.

27. Hayashi O, Hirahashi T, Katoh T, Miyajima H, Hirano T, Okuwaki Y. Class specific influence of dietary Spirulina platensis on antibody production in mice. J Nutr Sci Vitaminol. 1998;44:841-851.

28. Ishii K, Katoh T, Okuwaki Y, Hayashi O. Influence of dietary Spirulina platensis on IgA level in human saliva. J Kagawa Nutr Univ. 1999;30:27-33.

29. Chandra K. Nutrition and immune responses. Institute of Medicine. Military Strategies for Sustainment of Nutrition and Immune Function in the Field. National Academy Press; 1999:205-220.

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34. Zhi-gang Z, Zhi-li L, Xue-xian L. Study on the isolation, purification and antioxidation properties of polysaccharides from Spirulina maxima. Acta Botanica Sinica. 1997;39:77-81.

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36. Romay C, Armesto J, Remirez D, Gonzalez R, Ledon L, Garcia I. Antioxidant and anti-inflammatory properties of cphycocyanin from blue-green algae. Inflamm Res. 1998;47:36-41.

37. Romay C, Ledon N, Gonzalez R. Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflamm Res. 1998;334-338.

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39. Torres-Duran PV, Miranda-Zamora R, Paredes-Carbajal MC, Mascher D, Castillo B, Diaz-Zagoya JC, Juarez-Oropeza MA. Studies on the preventive effect of Spirulina maxima on fatty liver development induced by carbon tetrachloride, in the rat. J Ethnopaharmacol. 1999;64:141-147.

40. Bhat VB, Madyastha KM. C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro. Biochem Biophys Res Commun. 2000;1:20-25.

41. Rimbau V, Camins A, Romay C, Gonzalez R, Pallas M. Protective effect of C-phycocyanin against kainic acidinduced neuronal damage in rat hippocampus. Neuroscience Letters. 1999;276:75-78.

42. Romay C, Gonzalez R. Phycocyanin is an antioxidant protector of human erythrocytes against lysis by peroxyl radicals. J Pharm Pharmacol. 2000;52:367-368.

43. Hirata T, Tanaki M, Ooike M, Tsunomura T, Sagakuchi M. Antioxidant activities of phycocyanobillin prepared from Spirulina platensis. J Appl Phycol. 2000;435-439.

44. Reddy CM, Bhat VB, Kiranmai G, Reddy MN, Reddanna P, Madyastha KM. Selective inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensis. Biochem Biophys Res Commun. 2000;3:599-603.

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49. Schwartz J, Troxler RF, Saffer BG. Algae-derived phycocyanine is both cytostatic and cytotoxic to oral squamous cell carcinoma (human or hamster). J Dent Res. 1987;66:160.

50. Schwartz J, Shklar G, Reid S, Trickler D. Prevention of experimental oral cancer by extracts of Spirulina-Dunaliela algae. Nutr Cancer. 1988;11:127-134.

51. Lisheng L, Baojiang G, Jihong R, Guangquan Q, Botang Wu. Inhibitive effect and mechanism of polysaccharide of Spirulina platensis on transplanted tumor in mice. Marine Sciences. 1991;5:33-38.

52. Chen F, Zhang Q. Inhibitive effects of Spirulina on aberrant crypts in colon induced by dimethylhydrazine. Zhongua Yu Fang Yi Xue Za Zhi. 1995;29:13-17.

53. Mishima T, Murata J, Toyoshima M, Fujii K, Nakajima M, Hayashi T, Kato T, Saiki I. Inhibition of tumor invasion and metastasis by calcium spirulan (Ca-SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis. Clin Exp Metastasis.1998;16:541-550.

54. Liu Y, Xu L, Cheng N, Lin L, Zhang C. Inhibitory effect of phycocyanin from Spirulina platensis on the growth of human leukemia K562 cells. J Appl Phycol. 2000;12:125-130.

55. Dainippon Ink & Chemicals, Inc. (DIC). Anti-tumoral agents containing phycobillin. Japanese Patent #58-65216. 1983.

56. Qishen P, Baojiang G, Rhong R. Enhancement of endonuclease activity and repair of DNA synthesis by polysaccharide of Spirulina platensis. Chinese Genetics Journal (Acta Genetica Sinica) 1988;15:33374-33381.

57. Qishen P, Baojiang G, Kolman A. Radioprotective effect of extract from Spirulina platensis in mouse bone marrow cells studied by using the micronucleus test. Toxicol Letters. 1989;48:165-169.

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63. Gustafson KR, Cardellina JH II, Fuller RW, Weslow OS, Kiser RF, Snader KM, Paterson GM, Boyd MR. AIDS-antiviral sulfolipids from cyanobacteria (blue green algae). J Natl Cancer Inst. 1989; 81: 1254-1258.

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65. Hayashi K, Hayashi T, Morita N. An extract from Spirulina platensis is a selective inhibitor of Herpes simplex virus type 1 penetration into HeLa cells. Phytother Res. 1993;7:76-80.

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69. Hayakawa Y, Hayashi T, Hayashi K, Ozawa T, Niiya K, Sakuragawa N. Heparin cofactor II-dependent antithrombin activity of calcium spirulan. Blood Coagul Fibrinolysis. 1996;7:554-560.

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77. Iwata K, Inayama T, Kato T. Effects of Spirulina platensis on plasma lipoprotein lipase activity in fructose-induced hyperlipidemia in rats. J Nutr Sci Vitaminol. 1990;36:165-171.

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